ISDA: 4O8Z

Deposition Date 2013-12-31

Release Date 2015-04-22

Last Version Date 2023-11-08

Entry Detail

PDB ID:

4O8Z

Keywords:

HYDROLASE

Title:

Crystal structure of human SIRT3 in complex with compound (2-butylbenzofuran-3-yl)(4-(2-(diethylamino)ethoxy)-3,5-diiodophenyl)methanone

Biological Source:

Source Organism(s):

Homo sapiens (Taxon ID: 9606)

Expression System(s):

Escherichia coli

Method Details:

Experimental Method:

X-RAY DIFFRACTION

Resolution:

2.00 Å

R-Value Free:

0.20

R-Value Work:

0.16

R-Value Observed:

0.16

Space Group:

P 65

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Macromolecular Entities

Structures with similar UniProt ID

Protein Blast

Polymer Type:polypeptide(L)
Molecule:NAD-dependent protein deacety
Gene (Uniprot):SIRT3
Chain IDs:A
Chain Length:303
Number of Molecules:1
Biological Source:Homo sapiens

UniProt ID:Q9NTG7 Pfam ID:PF02146 EC:2.3.1.24

Ligand Molecules

BBI

Primary Citation

Crystal structure of human SIRT3 in complex with compound (2-butylbenzofuran-3-yl)(4-(2-(diethylamino)ethoxy)-3,5-diiodophenyl)methanone

Liu, B.Show

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Primary Citation of related structures

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