ISDA: 4N11

Deposition Date 2013-10-03

Release Date 2014-10-08

Last Version Date 2024-03-20

Entry Detail

PDB ID:

4N11

Keywords:

OXIDOREDUCTASE

Title:

Crystal structure of plasmodium falciparum reduced glutaredoxin 1 (PfGrx1) complexed with cisplatin

Biological Source:

Source Organism(s):

Plasmodium falciparum (Taxon ID: 36329)

Expression System(s):

Escherichia coli

Method Details:

Experimental Method:

X-RAY DIFFRACTION

Resolution:

1.97 Å

R-Value Free:

0.20

R-Value Work:

0.15

R-Value Observed:

0.16

Space Group:

P 32 2 1

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Macromolecular Entities

Structures with similar UniProt ID

Structural Superimposition Protein Blast

Polymer Type:polypeptide(L)
Molecule:Glutaredoxin
Gene (Uniprot):PF3D7_0306300
Chain IDs:A
Chain Length:111
Number of Molecules:1
Biological Source:Plasmodium falciparum

UniProt ID:Q9NLB2 Pfam ID:PF00462 EC:1.20.4.1

Ligand Molecules

CPT

MPD

MPO

Primary Citation

Interaction of Cisplatin with plasmodium falciparum Glutaredoxin 1

Yogavel, M, Tripathi, T, Rahlfs, S, Becker, K, Sharma, A.Show

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Primary Citation of related structures

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