ISDA: 4FKY

Deposition Date 2012-06-13

Release Date 2012-06-27

Last Version Date 2026-03-18

Entry Detail

PDB ID:

4FKY

Keywords:

TRANSFERASE

Title:

Crystal structure of nucleoside diphosphate kinase B from Trypanosoma brucei bound to GTP

Biological Source:

Source Organism(s):

Trypanosoma brucei brucei (Taxon ID: 999953)

Expression System(s):

Escherichia coli

Method Details:

Experimental Method:

X-RAY DIFFRACTION

Resolution:

1.95 Å

R-Value Free:

0.18

R-Value Work:

0.14

R-Value Observed:

0.14

Space Group:

C 2 2 21

Download Validation Report

Macromolecular Entities

Structures with similar UniProt ID

Protein Blast

Polymer Type:polypeptide(L)
Molecule:Nucleoside diphosphate kinase
Gene (Uniprot):Tb11.01.7800
Chain IDs:A, B, C
Chain Length:161
Number of Molecules:3
Biological Source:Trypanosoma brucei brucei

UniProt ID:Q381H3 Pfam ID:PF00334

Ligand Molecules

GDP

MPD

Primary Citation

Structural and Functional Analyses of Trypanosoma brucei Nucleoside Diphosphate Kinase

Makori, P, Boeckman, M.P, David, H.S, Payne, F, Gatling, M, Greer, C, Hayes, D, Jefferson, A, Maxwell, M, Smith, C, Watson, J, Williams, L, Barkley, J, Pepper, C, Zininga, T, Subramanian, S, Abramov, A, Gardberg, A.S, Edwards, T.E, Staker, B.L, Stewart, L.J, Myler, P.J, Asojo, O.A, Jeje, O, Fanucchi, S, Achilonu, I, Smith, C.L, Chakafana, G.Show

Acs Omega ? ? ? (2026)

DOI: 10.1021/acsomega.5c11614

Primary Citation of related structures

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