4DYM image
Deposition Date 2012-02-29
Release Date 2012-03-21
Last Version Date 2023-09-13
Entry Detail
PDB ID:
4DYM
Title:
Crystal structure of the ACVR1 kinase domain in complex with the imidazo[1,2-b]pyridazine inhibitor K00135
Biological Source:
Source Organism(s):
Homo sapiens (Taxon ID: 9606)
Expression System(s):
Method Details:
Experimental Method:
Resolution:
2.42 Å
R-Value Free:
0.27
R-Value Work:
0.21
R-Value Observed:
0.22
Space Group:
C 2 2 21
Macromolecular Entities
Structures with similar UniProt ID
Protein Blast
Polymer Type:polypeptide(L)
Molecule:Activin receptor type-1
Gene (Uniprot):ACVR1
Mutagens:R206H
Chain IDs:A
Chain Length:301
Number of Molecules:1
Biological Source:Homo sapiens
Primary Citation
Crystal structure of the ACVR1 kinase domain in complex with the imidazo[1,2-b]pyridazine inhibitor K00135
To be published ? ? ? (?)
Primary Citation of related structures
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