45CX image
Deposition Date 2026-08-24
Release Date 2026-10-21
Last Version Date 2026-10-21
Entry Detail
PDB ID:
45CX
Keywords:
LIGASE
Title:
CRYSTAL STRUCTURE OF LYSYL-TRNA SYNTHETASE FROM PLASMODIUM FALCIPARUM COMPLEXED WITH LYS-AMS
Biological Source:
Source Organism(s):
Plasmodium falciparum 3D7 (Taxon ID: 36329)
Expression System(s):
Escherichia coli
Method Details:
Experimental Method:
X-RAY DIFFRACTION
Resolution:
2.87 Å
R-Value Free:
0.26
R-Value Work:
0.21
R-Value Observed:
0.21
Space Group:
P 21 2 21
45CX validation report missing
Macromolecular Entities
Structures with similar UniProt ID
Structural Superimposition Protein Blast
Polymer Type:polypeptide(L)
Molecule:Lysine--tRNA ligase
Gene (Uniprot):PF3D7_1350100
Chain IDs:A (auth: B), B (auth: A), C (auth: D), D (auth: C)
Chain Length:507
Number of Molecules:4
Biological Source:Plasmodium falciparum 3D7
UniProt ID:Q8IDJ8 EC:6.1.1.6
Ligand Molecules
FMT
KAA
MLA
Primary Citation
Dual-Site Binding of an Aminoacyl-Adenylate Mimetic Stabilizes an Inactive Conformation of Plasmodium falciparum Lysyl-tRNA Synthetase
To Be Published ? ? ? (?)
Primary Citation of related structures
45CX
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