3PFV image
Deposition Date 2010-10-29
Release Date 2010-12-08
Last Version Date 2024-11-20
Entry Detail
PDB ID:
3PFV
Keywords:
LIGASE/PROTEIN BINDING
Title:
Crystal structure of Cbl-b TKB domain in complex with EGFR pY1069 peptide
Biological Source:
Source Organism(s):
Homo sapiens (Taxon ID: 9606)
Expression System(s):
Escherichia coli
Method Details:
Experimental Method:
X-RAY DIFFRACTION
Resolution:
2.27 Å
R-Value Free:
0.26
R-Value Work:
0.21
R-Value Observed:
0.21
Space Group:
P 1 21 1
3PFV validation report missing
Macromolecular Entities
Structures with similar UniProt ID
Protein Blast
Polymer Type:polypeptide(L)
Molecule:E3 ubiquitin-protein ligase C
Gene (Uniprot):CBLB
Chain IDs:A, B
Chain Length:315
Number of Molecules:2
Biological Source:Homo sapiens
UniProt ID:Q13191 Pfam ID:PF02262, PF02761, PF02762 EC:6.3.2.-
Structures with similar UniProt ID
Protein Blast
Polymer Type:polypeptide(L)
Molecule:11-meric peptide from Epiderm
Gene (Uniprot):EGFR
Chain IDs:C, D
Chain Length:11
Number of Molecules:2
Biological Source:Homo sapiens
UniProt ID:P00533 EC:2.7.10.1
Modified Residue
Compound ID Chain ID Parent Comp ID Details 2D Image
PTR C TYR O-PHOSPHOTYROSINE
Ligand Molecules
CL
EDO
NA
PG4
SO4
Primary Citation
Crystal structure of Cbl-b TKB domain in complex with EGFR pY1069 peptide
To be published ? ? ? (?)
Primary Citation of related structures
3PFV
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