3PDQ image
Deposition Date 2010-10-23
Release Date 2011-03-30
Last Version Date 2023-11-01
Entry Detail
PDB ID:
3PDQ
Title:
Crystal structure of JMJD2A complexed with bipyridyl inhibitor
Biological Source:
Source Organism(s):
Homo sapiens (Taxon ID: 9606)
Expression System(s):
Method Details:
Experimental Method:
Resolution:
1.99 Å
R-Value Free:
0.20
R-Value Work:
0.16
R-Value Observed:
0.16
Space Group:
P 21 21 2
Macromolecular Entities
Structures with similar UniProt ID
Protein Blast
Polymer Type:polypeptide(L)
Molecule:Lysine-specific demethylase 4
Gene (Uniprot):KDM4A
Chain IDs:A, B
Chain Length:381
Number of Molecules:2
Biological Source:Homo sapiens
Primary Citation
Inhibition of histone demethylases by 4-carboxy-2,2'-bipyridyl compounds
ChemMedChem 6 759 764 (2011)
PMID: 21412984 DOI: 10.1002/cmdc.201100026
Primary Citation of related structures
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