ISDA: 3LCR

Deposition Date 2010-01-11

Release Date 2010-08-18

Last Version Date 2024-02-21

Entry Detail

PDB ID:

3LCR

Keywords:

HYDROLASE

Title:

Thioesterase from Tautomycetin Biosynthhetic Pathway

Biological Source:

Source Organism(s):

Streptomyces sp. CK4412 (Taxon ID: 404220)

Expression System(s):

Escherichia coli

Method Details:

Experimental Method:

X-RAY DIFFRACTION

Resolution:

2.00 Å

R-Value Free:

0.23

R-Value Work:

0.18

R-Value Observed:

0.18

Space Group:

P 1 21 1

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Macromolecular Entities

Structures with similar UniProt ID

Protein Blast

Polymer Type:polypeptide(L)
Molecule:Tautomycetin biosynthetic PKS
Chain IDs:A, B
Chain Length:319
Number of Molecules:2
Biological Source:Streptomyces sp. CK4412

UniProt ID:A4KCE5 Pfam ID:PF00975

Ligand Molecules

DMS

FMT

Primary Citation

Biochemical and structural characterization of the tautomycetin thioesterase: analysis of a stereoselective polyketide hydrolase.

Scaglione, J.B, Akey, D.L, Sullivan, R, Kittendorf, J.D, Rath, C.M, Kim, E.S, Smith, J.L, Sherman, D.H.Show

Angew. Chem. Int. Ed. Engl. 49 5726 5730 (2010)

PMID: 20623733 DOI: 10.1002/anie.201000032

Primary Citation of related structures

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