3IMC image
Deposition Date 2009-08-10
Release Date 2009-10-13
Last Version Date 2023-09-06
Entry Detail
PDB ID:
3IMC
Keywords:
Title:
Crystal Structure of Mycobacterium Tuberculosis Pantothenate Synthetase at 1.6 Ang resolution in complex with fragment compound 5-methoxyindole, sulfate and glycerol
Biological Source:
Source Organism(s):
Expression System(s):
Method Details:
Experimental Method:
Resolution:
1.60 Å
R-Value Free:
0.20
R-Value Work:
0.16
R-Value Observed:
0.16
Space Group:
P 1 21 1
Macromolecular Entities
Structures with similar UniProt ID
Protein Blast
Polymer Type:polypeptide(L)
Molecule:Pantothenate synthetase
Mutagens:T2A, E77G
Chain IDs:A, B
Chain Length:301
Number of Molecules:2
Biological Source:Mycobacterium tuberculosis
Primary Citation
Application of fragment growing and fragment linking to the discovery of inhibitors of Mycobacterium tuberculosis pantothenate synthetase.
Angew. Chem. Int. Ed. Engl. 48 8452 8456 (2009)
PMID: 19780086 DOI: 10.1002/anie.200903821
Primary Citation of related structures
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