ISDA: 3COS

Deposition Date 2008-03-29

Release Date 2008-04-15

Last Version Date 2023-08-30

Entry Detail

PDB ID:

3COS

Keywords:

OXIDOREDUCTASE

Title:

Crystal structure of human class II alcohol dehydrogenase (ADH4) in complex with NAD and Zn

Biological Source:

Source Organism(s):

Homo sapiens (Taxon ID: 9606)

Expression System(s):

Escherichia coli bl21(de3)

Method Details:

Experimental Method:

X-RAY DIFFRACTION

Resolution:

2.10 Å

R-Value Free:

0.20

R-Value Work:

0.16

R-Value Observed:

0.16

Space Group:

P 1 21 1

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Macromolecular Entities

Structures with similar UniProt ID

Structural Superimposition Protein Blast

Polymer Type:polypeptide(L)
Molecule:Alcohol dehydrogenase 4
Gene (Uniprot):ADH4
Chain IDs:A, B, C, D
Chain Length:381
Number of Molecules:4
Biological Source:Homo sapiens

UniProt ID:P08319 Pfam ID:PF00107, PF08240 EC:1.1.1.1

Ligand Molecules

ACY

EDO

NAD

Primary Citation

Crystal structure of human class II alcohol dehydrogenase (ADH4) in complex with NAD and Zn.

Kavanagh, K.L, Shafqat, N, Yue, W, von Delft, F, Bishop, S, Roos, A, Murray, J, Edwards, A.M, Arrowsmith, C.H, Bountra, C, Oppermann, U.Show

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Primary Citation of related structures

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