ISDA: 36UP

Deposition Date 2026-07-01

Release Date 2026-10-07

Last Version Date 2026-10-07

Entry Detail

PDB ID:

36UP

Keywords:

DNA BINDING PROTEIN/DNA

Title:

S. aureus DNA Gyrase in complex with OSUAB-0284 and DNA

Biological Source:

Source Organism(s):

Staphylococcus aureus subsp. aureus N315 (Taxon ID: 158879)
synthetic construct (Taxon ID: 32630)

Expression System(s):

Escherichia coli bl21

Method Details:

Experimental Method:

ELECTRON MICROSCOPY

Resolution:

2.75 Å

Aggregation State:

PARTICLE

Reconstruction Method:

SINGLE PARTICLE

Download Validation Report

Macromolecular Entities

Structural Superimposition Protein Blast

Polymer Type:polypeptide(L)
Molecule:DNA Gyrase subunit B, DNA Gyr
Chain IDs:C (auth: A), D (auth: B)
Chain Length:693
Number of Molecules:2
Biological Source:Staphylococcus aureus subsp. aureus N315

Polymer Type:polydeoxyribonucleotide
Molecule:DNA (5'-D(P*AP*GP*CP*CP*GP*TP
Chain IDs:A (auth: C), B (auth: D)
Chain Length:20
Number of Molecules:2
Biological Source:synthetic construct

Ligand Molecules

A1DL2

Primary Citation

In vitro and in vivo activity of OSUAB-0284, a preclinical candidate for Staphylococcus aureus infection

Mann, C.A, West, J.C, Cassel, S.R, Wheat, C.T, Landgraf, A.D, Tomkovicz, J.V, Zhao, X, Eaton, S, Dellos-Nolan, S, Baldridge, I, Srivastava, P, Kennedy-Mendez, A, Pillar, C.M, Hufnagel, D.A, Kebriaei, R, Bell, C.E, Wozniak, D.J, Yalowich, J.C, Mitton-Fry, M.J.Show

To Be Published ? ? ? (?)

Primary Citation of related structures

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