36NB image
Deposition Date 2026-06-19
Release Date 2026-08-19
Last Version Date 2026-08-19
Entry Detail
PDB ID:
36NB
Keywords:
DNA BINDING PROTEIN
Title:
Crystal structure of the NKX2-1 homeodomain bound to a palindromic DNA recognition sequence
Biological Source:
Source Organism(s):
Homo sapiens (Taxon ID: 9606)
Expression System(s):
Escherichia coli bl21
Method Details:
Experimental Method:
X-RAY DIFFRACTION
Resolution:
3.26 Å
R-Value Free:
0.29
R-Value Work:
0.22
R-Value Observed:
0.22
Space Group:
P 1 21 1
36NB validation report missing
Macromolecular Entities
Polymer Type:polypeptide(L)
Molecule:Homeobox protein Nkx-2.1
Chain IDs:A, B, C, D
Chain Length:60
Number of Molecules:4
Biological Source:Homo sapiens
Polymer Type:polydeoxyribonucleotide
Molecule:DAN TCAAGTGGGCCCCACTTGA
Chain IDs:E, G
Chain Length:19
Number of Molecules:2
Biological Source:Homo sapiens
Polymer Type:polydeoxyribonucleotide
Molecule:DNA TCAAGTGGGGCCCACTTGA
Chain IDs:F, H
Chain Length:19
Number of Molecules:2
Biological Source:Homo sapiens
Primary Citation
Crystal structure of the NKX2-1 homeodomain bound to a palindromic DNA recognition sequence.
Acta Crystallogr.,Sect.F ? ? ? (2026)
PMID: 42565819 DOI: 10.1107/S2053230X26007466
Primary Citation of related structures
36NB
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