ISDA: 36LX

Deposition Date 2026-06-17

Release Date 2026-07-15

Last Version Date 2026-07-15

Entry Detail

PDB ID:

36LX

Keywords:

APOPTOSIS

Title:

Crystal Structure of mini-binder MB03-ds

Biological Source:

Source Organism(s):

synthetic construct (Taxon ID: 32630)

Expression System(s):

Escherichia coli

Method Details:

Experimental Method:

X-RAY DIFFRACTION

Resolution:

2.10 Å

R-Value Free:

0.28

R-Value Work:

0.25

R-Value Observed:

0.25

Space Group:

P 21 21 21

Download Validation Report

Macromolecular Entities

Structural Superimposition Protein Blast

Polymer Type:polypeptide(L)
Molecule:MB03-ds
Chain IDs:A, B, C, D
Chain Length:67
Number of Molecules:4
Biological Source:synthetic construct

Primary Citation

Orally available designed miniproteins inhibit enterotoxigenic Bacteroides fragilis pathology by blocking toxin receptor binding.

Srinivas, P, Adebomi, V, Markiewicz, S.M, Wang, K, Chac, D, Lindenauer, K, Huber, N, Tao, Z, Luong, P, Rettie, S.A, Smith, M.W, Bera, A.K, Kang, A, Nguyen, H, Schneider, M, Wang, Y, Peterson, S.B, Dong, M, Weil, A.A, Bhardwaj, G, Mougous, J.D.Show

Biorxiv ? ? ? (2026)

PMID: 42395444 DOI: 10.64898/2026.06.22.733822

Primary Citation of related structures

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