ISDA: 35WK

Deposition Date 2026-05-20

Release Date 2026-09-23

Last Version Date 2026-09-23

Entry Detail

PDB ID:

35WK

Keywords:

TRANSFERASE

Title:

Crystal structure of the core catalytic domain of human inositol phosphate multikinase in complex with an inhibitor UNC7844

Biological Source:

Source Organism(s):

Homo sapiens (Taxon ID: 9606)

Expression System(s):

Escherichia coli

Method Details:

Experimental Method:

X-RAY DIFFRACTION

Resolution:

1.65 Å

R-Value Free:

0.25

R-Value Work:

0.21

Space Group:

P 42 21 2

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Macromolecular Entities

Structures with similar UniProt ID

Structural Superimposition Protein Blast

Polymer Type:polypeptide(L)
Molecule:Inositol polyphosphate multik
Gene (Uniprot):IPMK
Chain IDs:A
Chain Length:0
Number of Molecules:1
Biological Source:Homo sapiens

UniProt ID:Q8NFU5 Pfam ID:PF03770 EC:2.7.1.151

Ligand Molecules

A1DH6

Primary Citation

Targeting host inositol (pyro)phosphate pathway for inhibition of coronavirus replication

Shats, I, Wang, H.Show

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Primary Citation of related structures

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