32QS image
Deposition Date 2026-07-21
Release Date 2026-07-29
Last Version Date 2026-08-12
Entry Detail
PDB ID:
32QS
Keywords:
LIGASE
Title:
Ternary complex structure of TRIM21 (PRYSPRY) and BRD4 (BD1) bound to PROTAC 1b
Biological Source:
Source Organism(s):
Homo sapiens (Taxon ID: 9606)
Expression System(s):
Escherichia coli
Method Details:
Experimental Method:
X-RAY DIFFRACTION
Resolution:
2.70 Å
R-Value Free:
0.26
R-Value Work:
0.21
Space Group:
I 1 2 1
32QS validation report missing
Macromolecular Entities
Structures with similar UniProt ID
Structural Superimposition Protein Blast
Polymer Type:polypeptide(L)
Molecule:E3 ubiquitin-protein ligase T
Gene (Uniprot):TRIM21
Chain IDs:A
Chain Length:0
Number of Molecules:1
Biological Source:Homo sapiens
UniProt ID:P19474 Pfam ID:PF13765, PF00622 EC:2.3.2.27
Structures with similar UniProt ID
Structural Superimposition Protein Blast
Polymer Type:polypeptide(L)
Molecule:Bromodomain-containing protei
Gene (Uniprot):BRD4
Chain IDs:B
Chain Length:0
Number of Molecules:1
Biological Source:Homo sapiens
UniProt ID:O60885 Pfam ID:PF00439
Ligand Molecules
A1KEC
PEG
Primary Citation
Ternary complex structure of TRIM21 (PRYSPRY) and BRD4 (BD1) bound to PROTAC 1b
To Be Published ? ? ? (?)
Primary Citation of related structures
32QS
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