ISDA: 32NZ

Deposition Date 2026-07-17

Release Date 2026-08-12

Last Version Date 2026-08-12

Entry Detail

PDB ID:

32NZ

Keywords:

PROTEIN BINDING

Title:

An activating H90 ScFv bound to the hyaluronan-binding domain of human CD44

Biological Source:

Source Organism(s):

synthetic construct (Taxon ID: 32630)
Homo sapiens (Taxon ID: 9606)

Expression System(s):

Escherichia coli

Method Details:

Experimental Method:

X-RAY DIFFRACTION

Resolution:

1.80 Å

R-Value Free:

0.24

R-Value Work:

0.19

Space Group:

P 41 21 2

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Macromolecular Entities

Polymer Type:polypeptide(L)
Molecule:H90 scFv
Chain IDs:A
Chain Length:278
Number of Molecules:1
Biological Source:synthetic construct

Polymer Type:polypeptide(L)
Molecule:CD44 antigen
Chain IDs:B
Chain Length:134
Number of Molecules:1
Biological Source:Homo sapiens

Ligand Molecules

Primary Citation

An activating H90 ScFv bound to the hyaluronan-binding domain of human CD44

Bradshaw, W.J, Wilkes, A.J.R, Katis, V.L, Newman, J.A, Gileadi, O.Show

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Primary Citation of related structures

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