ISDA: 32NU

Deposition Date 2026-07-17

Release Date 2026-09-02

Last Version Date 2026-09-02

Entry Detail

PDB ID:

32NU

Keywords:

VIRAL PROTEIN

Title:

Crystal structure of SARS-CoV-2 Mpro in complex with NSC47924

Biological Source:

Source Organism(s):

Severe acute respiratory syndrome coronavirus 2 (Taxon ID: 2697049)

Expression System(s):

Escherichia coli

Method Details:

Experimental Method:

X-RAY DIFFRACTION

Resolution:

1.90 Å

R-Value Free:

0.28

R-Value Work:

0.22

Space Group:

C 1 2 1

Download Validation Report

Macromolecular Entities

Polymer Type:polypeptide(L)
Molecule:3C-like proteinase nsp5
Chain IDs:A
Chain Length:306
Number of Molecules:1
Biological Source:Severe acute respiratory syndrome coronavirus 2

Ligand Molecules

A1KEA

Primary Citation

Investigating the Binding Mode of a Naphthol-Based Inhibitor Targeting SARS-CoV-2 Main Protease.

Akrani, I, El Kilani, H, Touret, F, Kouvali, S, Gourni, V, Tsoka, A, Tsetis, J.K, Vorgias, C, Hilgenfeld, R, Kostakis, I.K, Myrianthopoulos, V, Mikros, E.Show

Chemmedchem 21 e70448 e70448 (2026)

PMID: 42647061 DOI: 10.1002/cmdc.70448

Primary Citation of related structures

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