ISDA: 32HC

Deposition Date 2026-07-09

Release Date 2026-08-26

Last Version Date 2026-08-26

Entry Detail

PDB ID:

32HC

Keywords:

HYDROLASE

Title:

PARP9 Macro Domain 2 P347G mutant in complex with ADPr

Biological Source:

Source Organism(s):

Homo sapiens (Taxon ID: 9606)

Expression System(s):

Escherichia coli bl21(de3)

Method Details:

Experimental Method:

X-RAY DIFFRACTION

Resolution:

1.40 Å

R-Value Free:

0.16

R-Value Work:

0.12

R-Value Observed:

0.12

Space Group:

P 43 21 2

Download Validation Report

Macromolecular Entities

Polymer Type:polypeptide(L)
Molecule:Protein mono-ADP-ribosyltrans
Mutagens:P347G
Chain IDs:A
Chain Length:197
Number of Molecules:1
Biological Source:Homo sapiens

Ligand Molecules

APR

AR6

Primary Citation

So different, yet so similar: the paradigm of PARP9 macro domain paralogs

Fourkiotis, K.N, Sideras-Bisdekis, C, Tsika, C.A, Fish, A, Kravvariti, P.K, Tsatsouli, S.A, Perrakis, A, Chikunova, A, Spyroulias, A.G.Show

To Be Published ? ? ? (?)

Primary Citation of related structures

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