31ZI image
Deposition Date 2026-06-30
Release Date 2026-10-21
Last Version Date 2026-10-21
Entry Detail
PDB ID:
31ZI
Keywords:
DNA BINDING PROTEIN
Title:
Crystal structure of RAD52 N-terminal domain in complex with fragment Z271005800
Biological Source:
Source Organism(s):
Homo sapiens (Taxon ID: 9606)
Expression System(s):
Escherichia coli bl21(de3)
Method Details:
Experimental Method:
X-RAY DIFFRACTION
Resolution:
2.10 Å
R-Value Free:
0.21
R-Value Work:
0.18
R-Value Observed:
0.18
Space Group:
P 21 21 21
31ZI validation report missing
Macromolecular Entities
Structures with similar UniProt ID
Structural Superimposition Protein Blast
Polymer Type:polypeptide(L)
Molecule:DNA repair protein RAD52 homo
Gene (Uniprot):RAD52
Mutagens:K102A, K133A
Chain IDs:A, B, C, D, E, F, G, H, I, J, K, L, M, N, O, P, Q, R, S, T, U, V
Chain Length:215
Number of Molecules:22
Biological Source:Homo sapiens
UniProt ID:P43351
Ligand Molecules
A1KCG
CL
EDO
MG
Primary Citation
Integrating Fragment Screening and Covalent Chemistry to Drug DNA-Binding Proteins: RAD52 as a Case Study.
J.Am.Chem.Soc. ? ? ? (2026)
PMID: 42854208 DOI: 10.1021/jacs.6c16278
Primary Citation of related structures
31XQ
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