ISDA: 31SY

Deposition Date 2026-06-23

Release Date 2026-09-30

Last Version Date 2026-09-30

Entry Detail

PDB ID:

31SY

Keywords:

HYDROLASE

Title:

Human wild-type LONP1 bound to PZL-26

Biological Source:

Source Organism(s):

Homo sapiens (Taxon ID: 9606)

Expression System(s):

Escherichia coli

Method Details:

Experimental Method:

ELECTRON MICROSCOPY

Resolution:

3.00 Å

Aggregation State:

PARTICLE

Reconstruction Method:

SINGLE PARTICLE

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Macromolecular Entities

Structures with similar UniProt ID

Structural Superimposition Protein Blast

Polymer Type:polypeptide(L)
Molecule:Lon protease homolog, mitocho
Gene (Uniprot):LONP1
Chain IDs:A, B, C, D, E, F
Chain Length:0
Number of Molecules:6
Biological Source:Homo sapiens

UniProt ID:P36776 Pfam ID:PF02190, PF00004, PF22667, PF05362 EC:3.4.21.53

Ligand Molecules

A1KDX

Primary Citation

A selective inhibitor reveals roles for LONP1 in mitochondrial proteostasis and OXPHOS dependencies

Szilagyi, Z, Michon, P, Pardo-Hernandez, C, Sacultanu, M, Miralles Fuste, J, Griffin, A.M, Charifson, P.S, Phan, C, Shi, Y, Kern, G, Martinez Botella, G, Keating, T.A, Macao, B, Larsson, N.G, Falkenberg, M, Green, J, Gustafsson, C.M.Show

To Be Published ? ? ? (?)

Primary Citation of related structures

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