ISDA: 31RQ

Deposition Date 2026-06-18

Release Date 2026-09-23

Last Version Date 2026-09-23

Entry Detail

PDB ID:

31RQ

Keywords:

TRANSFERASE

Title:

Mycobacterium abscessus Phophopantheteinyl transferase PptAb in complex with 2-((3,4-dihydro-2H-pyrrol-5-yl)amino)phenol (compound 2a)

Biological Source:

Source Organism(s):

Mycobacteroides abscessus ATCC 19977 (Taxon ID: 561007)

Expression System(s):

Escherichia coli bl21(de3)

Method Details:

Experimental Method:

X-RAY DIFFRACTION

Resolution:

1.08 Å

R-Value Free:

0.17

R-Value Work:

0.14

R-Value Observed:

0.15

Space Group:

P 21 21 2

Download Validation Report

Macromolecular Entities

Structures with similar UniProt ID

Structural Superimposition Protein Blast

Polymer Type:polypeptide(L)
Molecule:Possible 4'-phosphopantethein
Gene (Uniprot):MAB_3117c
Chain IDs:A
Chain Length:0
Number of Molecules:1
Biological Source:Mycobacteroides abscessus ATCC 19977

UniProt ID:B1MD73 Pfam ID:PF17837, PF01648

Ligand Molecules

A1KBD

COA

Primary Citation

From serendipitous reaction discovery to antimycobacterial opportunities: general access to scarcely reported 2-((pyrrolin-5-yl)amino)phenols.

El Faudel, D, Publicola, G, Carayon, C, Robert, F, Toppan, C, Alric, J, Carivenc, C, Mourey, L, Nahoum, V, Ballereau, S, Maveyraud, L, Genisson, Y.Show

Org.Biomol.Chem. ? ? ? (2026)

PMID: 42704347 DOI: 10.1039/d6ob01100d

Primary Citation of related structures

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