ISDA: 31IC

Deposition Date 2026-06-05

Release Date 2026-07-01

Last Version Date 2026-07-01

Entry Detail

PDB ID:

31IC

Keywords:

MEMBRANE PROTEIN

Title:

Structure of human excitatory amino acid transporter 3 (EAAT3) in complex with B11 nanobody

Biological Source:

Source Organism(s):

Homo sapiens (Taxon ID: 9606)
Vicugna pacos (Taxon ID: 30538)

Expression System(s):

Spodoptera frugiperda, Escherichia coli mc1061

Method Details:

Experimental Method:

ELECTRON MICROSCOPY

Resolution:

3.50 Å

Aggregation State:

PARTICLE

Reconstruction Method:

SINGLE PARTICLE

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Macromolecular Entities

Structures with similar UniProt ID

Protein Blast

Polymer Type:polypeptide(L)
Molecule:Excitatory amino acid transpo
Gene (Uniprot):SLC1A1
Mutagens:L92V
Chain IDs:A, B, C
Chain Length:487
Number of Molecules:3
Biological Source:Homo sapiens

UniProt ID:P43005 Pfam ID:PF00375

Protein Blast

Polymer Type:polypeptide(L)
Molecule:B11 nanobody
Chain IDs:D
Chain Length:166
Number of Molecules:1
Biological Source:Vicugna pacos

Ligand Molecules

Primary Citation

Structure of human excitatory amino acid transporter 3 (EAAT3) in complex with a nanobody

Li, A, Pike, A.C.W, Baronina, A, Rodstrom, K.E.J, Pascoa, T.C, Chi, G, Stefanic, S, Carpenter, E.P, Bullock, A.N, Dong, Y.Y, Sauer, D.B.Show

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Primary Citation of related structures

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