ISDA: 31DE

Deposition Date 2026-05-27

Release Date 2026-08-26

Last Version Date 2026-08-26

Entry Detail

PDB ID:

31DE

Keywords:

OXIDOREDUCTASE

Title:

Human Pyridoxine-5'-phosphate oxidase in complex with PLP-isoniazid in its active site

Biological Source:

Source Organism(s):

Homo sapiens (Taxon ID: 9606)

Expression System(s):

Escherichia coli 'bl21-gold(de3)plyss ag'

Method Details:

Experimental Method:

X-RAY DIFFRACTION

Resolution:

2.20 Å

R-Value Free:

0.23

R-Value Work:

0.17

Space Group:

P 31 2 1

Download Validation Report

Macromolecular Entities

Polymer Type:polypeptide(L)
Molecule:Pyridoxine-5'-phosphate oxida
Chain IDs:A
Chain Length:280
Number of Molecules:1
Biological Source:Homo sapiens

Ligand Molecules

2B9

FMN

PEG

Primary Citation

Evaluation of the therapeutic potential of pyridoxal 5'-phosphate hydrazones as anticancer agents

Graziani, C, Brufani, V, Fiorillo, A, Di Salvo, M, Tramoni, A, Chiocchiolini, F, Spande, S, Botakhanova, A, De Cecio, I, Bufalieri, F, Contestabile, R, Ferri, G, Di Marcotullio, L, Vetica, F, Paone, A, Borsatti, G, Cutruzzola, F, Fiorentino, F.Show

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Primary Citation of related structures

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