30LN image
Deposition Date 2026-05-04
Release Date 2026-09-02
Last Version Date 2026-09-02
Entry Detail
PDB ID:
30LN
Title:
Mouse cGAS in complex with DNA and pppGpA, crystallized in presence of Ap4G.
Biological Source:
Source Organism(s):
Expression System(s):
Method Details:
Experimental Method:
Resolution:
2.56 Å
R-Value Free:
0.24
R-Value Work:
0.21
R-Value Observed:
0.21
Space Group:
P 21 21 21
Macromolecular Entities
Polymer Type:polypeptide(L)
Molecule:Cyclic GMP-AMP synthase
Chain IDs:A, B
Chain Length:364
Number of Molecules:2
Biological Source:Mus musculus
Polymer Type:polydeoxyribonucleotide
Molecule:DNA (5'-D(*AP*TP*CP*TP*GP*TP*
Chain IDs:C, D, E, F
Chain Length:18
Number of Molecules:4
Biological Source:synthetic construct
Primary Citation
NUDT2 loss defines quantitative limits for dinucleoside polyphosphate action on the cGAS-STING-TBK1 axis
Biorxiv ? ? ? (2026)
DOI: 10.64898/2026.08.18.745545
Primary Citation of related structures
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