ISDA: 30KE

Deposition Date 2026-04-30

Release Date 2026-09-30

Last Version Date 2026-09-30

Entry Detail

PDB ID:

30KE

Keywords:

HYDROLASE

Title:

Crystal structure of human SIRT2 in complex with KMyrMe peptide and NAD+

Biological Source:

Source Organism(s):

Homo sapiens (Taxon ID: 9606)
synthetic construct (Taxon ID: 32630)

Expression System(s):

Escherichia coli

Method Details:

Experimental Method:

X-RAY DIFFRACTION

Resolution:

2.80 Å

R-Value Free:

0.26

R-Value Work:

0.22

R-Value Observed:

0.22

Space Group:

P 1 21 1

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Macromolecular Entities

Structures with similar UniProt ID

Structural Superimposition Protein Blast

Polymer Type:polypeptide(L)
Molecule:NAD-dependent protein deacety
Gene (Uniprot):SIRT2
Chain IDs:A
Chain Length:304
Number of Molecules:1
Biological Source:Homo sapiens

UniProt ID:Q8IXJ6 Pfam ID:PF02146 EC:2.3.1.286

Polymer Type:polypeptide(L)
Molecule:KMyrMe peptide
Chain IDs:B (auth: C)
Chain Length:7
Number of Molecules:1
Biological Source:synthetic construct

Ligand Molecules