30CP image
Deposition Date 2026-04-21
Release Date 2026-10-07
Last Version Date 2026-10-07
Entry Detail
PDB ID:
30CP
Keywords:
VIRAL PROTEIN
Title:
Structure of the Hepatitis C Virus E2 Core from Genotype 6a in Complex with Germline Reverted Variants of the Broadly Neutralizing Antibody AR3C
Biological Source:
Source Organism(s):
Homo sapiens (Taxon ID: 9606)
Recombinant Hepatitis C virus HK6a/JFH-1 (Taxon ID: 595609)
Expression System(s):
Homo sapiens
Method Details:
Experimental Method:
X-RAY DIFFRACTION
Resolution:
1.93 Å
R-Value Free:
0.24
R-Value Work:
0.20
R-Value Observed:
0.20
Space Group:
P 21 21 21
30CP validation report missing
Macromolecular Entities
Structural Superimposition Protein Blast
Polymer Type:polypeptide(L)
Molecule:HCV E2 envelope protein
Mutagens:N448D
Chain IDs:C (auth: D0A0)
Chain Length:189
Number of Molecules:1
Biological Source:Recombinant Hepatitis C virus HK6a/JFH-1
Structural Superimposition Protein Blast
Polymer Type:polypeptide(L)
Molecule:Fab AR3C GL heavy chain
Chain IDs:A (auth: H)
Chain Length:232
Number of Molecules:1
Biological Source:Homo sapiens
Structural Superimposition Protein Blast
Polymer Type:polypeptide(L)
Molecule:Fab AR3C GL light chain
Chain IDs:B (auth: L)
Chain Length:233
Number of Molecules:1
Biological Source:Homo sapiens
Ligand Molecules
NAG
PEG
Primary Citation
Structural and biochemical studies of the hepatitis C virus envelope proteins to promote germline-targeting vaccine design
To Be Published ? ? ? (?)
Primary Citation of related structures
30CP
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