30AF image
Deposition Date 2026-04-16
Release Date 2026-09-02
Last Version Date 2026-09-02
Entry Detail
PDB ID:
30AF
Keywords:
IMMUNE SYSTEM
Title:
Complex between IgE-Fc and anti-IgE Fab aeFab98
Biological Source:
Source Organism(s):
Homo sapiens (Taxon ID: 9606)
Oryctolagus cuniculus (Taxon ID: 9986)
Expression System(s):
Mus musculus, Homo sapiens
Method Details:
Experimental Method:
X-RAY DIFFRACTION
Resolution:
2.40 Å
R-Value Free:
0.22
R-Value Work:
0.19
R-Value Observed:
0.19
Space Group:
C 1 2 1
30AF validation report missing
Macromolecular Entities
Polymer Type:polypeptide(L)
Molecule:Isoform 1 of Immunoglobulin h
Chain IDs:A (auth: B), B (auth: A)
Chain Length:327
Number of Molecules:2
Biological Source:Homo sapiens
Polymer Type:polypeptide(L)
Molecule:aeFab98 heavy chain
Chain IDs:C (auth: H)
Chain Length:216
Number of Molecules:1
Biological Source:Oryctolagus cuniculus
Polymer Type:polypeptide(L)
Molecule:aeFab98 light chain
Chain IDs:D (auth: L)
Chain Length:214
Number of Molecules:1
Biological Source:Oryctolagus cuniculus
Ligand Molecules
ACT
EDO
GOL
PEG
Primary Citation
Anti-IgE Fab fragments that share a common epitope display markedly different functional activities
To Be Published ? ? ? (?)
Primary Citation of related structures
30AF
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