ISDA: 30AE

Deposition Date 2026-04-16

Release Date 2026-09-02

Last Version Date 2026-09-02

Entry Detail

PDB ID:

30AE

Keywords:

IMMUNE SYSTEM

Title:

Complex between IgE-Fc and anti-IgE Fab aeFab92

Biological Source:

Source Organism(s):

Oryctolagus cuniculus (Taxon ID: 9986)
Homo sapiens (Taxon ID: 9606)

Expression System(s):

Homo sapiens, Mus musculus

Method Details:

Experimental Method:

X-RAY DIFFRACTION

Resolution:

3.50 Å

R-Value Free:

0.28

R-Value Work:

0.24

R-Value Observed:

0.24

Space Group:

C 1 2 1

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Macromolecular Entities

Polymer Type:polypeptide(L)
Molecule:Isoform 1 of Immunoglobulin h
Chain IDs:C (auth: B), D (auth: A)
Chain Length:327
Number of Molecules:2
Biological Source:Homo sapiens

Polymer Type:polypeptide(L)
Molecule:aeFab92 heavy chain
Chain IDs:A (auth: H)
Chain Length:215
Number of Molecules:1
Biological Source:Oryctolagus cuniculus

Polymer Type:polypeptide(L)
Molecule:aeFab92 light chain
Chain IDs:B (auth: L)
Chain Length:214
Number of Molecules:1
Biological Source:Oryctolagus cuniculus

Ligand Molecules

Primary Citation

Anti-IgE Fab fragments that share a common epitope display markedly different functional activities

Davies, A.M, Drinkwater, N, Beavil, A.J, O'Dowd, V, Lightwood, D, Ceska, T, Henry, A.J, Sutton, B.J, McDonnell, J.M.Show

To Be Published ? ? ? (?)

Primary Citation of related structures

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