ISDA: 29ZM

Deposition Date 2026-04-16

Release Date 2026-05-06

Last Version Date 2026-05-06

Entry Detail

PDB ID:

29ZM

Keywords:

LIGASE

Title:

Crystal Structure of UDP-N-acetylmuramate-L-alanine ligase (MurC) from Pseudomonas aeruginosa in complex with compound OSA_001175 (WYH77)

Biological Source:

Source Organism(s):

Pseudomonas aeruginosa (Taxon ID: 287)

Expression System(s):

Escherichia coli bl21(de3)

Method Details:

Experimental Method:

X-RAY DIFFRACTION

Resolution:

2.40 Å

R-Value Free:

0.25

R-Value Work:

0.19

R-Value Observed:

0.19

Space Group:

P 21 21 21

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Macromolecular Entities

Structures with similar UniProt ID

Protein Blast

Polymer Type:polypeptide(L)
Molecule:UDP-N-acetylmuramate--L-alani
Gene (Uniprot):murC
Chain IDs:A, B
Chain Length:480
Number of Molecules:2
Biological Source:Pseudomonas aeruginosa

UniProt ID:Q9HW02 Pfam ID:PF01225, PF08245, PF02875

Ligand Molecules

A1J52

DMS

EDO

PEG

PO4

Primary Citation

Crystal Structure of UDP-N-acetylmuramate-L-alanine ligase (MurC) from Pseudomonas aeruginosa in complex with compound OSA_001175 (WYH77)

Quintanilla-Madronal, G, Lloyd, A.J, Wang, Y, Todd, M.H, Dowson, C.G, Diaz-Saez, L.Show

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