29RY image
Deposition Date 2026-04-02
Release Date 2026-07-29
Last Version Date 2026-07-29
Entry Detail
PDB ID:
29RY
Keywords:
TRANSFERASE
Title:
The crystal structure of the apo JAK2 kinase domain
Biological Source:
Source Organism(s):
Homo sapiens (Taxon ID: 9606)
Expression System(s):
Trichoplusia ni
Method Details:
Experimental Method:
X-RAY DIFFRACTION
Resolution:
1.75 Å
R-Value Free:
0.23
R-Value Work:
0.20
R-Value Observed:
0.20
Space Group:
C 1 2 1
29RY validation report missing
Macromolecular Entities
Structures with similar UniProt ID
Structural Superimposition Protein Blast
Polymer Type:polypeptide(L)
Molecule:Tyrosine-protein kinase JAK2
Gene (Uniprot):JAK2
Chain IDs:A
Chain Length:316
Number of Molecules:1
Biological Source:Homo sapiens
UniProt ID:O60674 Pfam ID:PF07714 EC:2.7.10.2
Modified Residue
Compound ID Chain ID Parent Comp ID Details 2D Image
PTR A TYR modified residue
Primary Citation
Janus kinase 2 activation loop as a regulator of catalysis and trans-activation.
Int.J.Biol.Macromol. 374 153276 153276 (2026)
PMID: 42409141 DOI: 10.1016/j.ijbiomac.2026.153276
Primary Citation of related structures
29RY
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