29RT image
Deposition Date 2026-04-01
Release Date 2026-07-22
Last Version Date 2026-07-22
Entry Detail
PDB ID:
29RT
Keywords:
MEMBRANE PROTEIN
Title:
Insulin receptor ecto-domain in inverted-U apo-conformation
Biological Source:
Source Organism(s):
Homo sapiens (Taxon ID: 9606)
Expression System(s):
Homo sapiens
Method Details:
Experimental Method:
ELECTRON MICROSCOPY
Resolution:
7.50 Å
Aggregation State:
PARTICLE
Reconstruction Method:
SINGLE PARTICLE
29RT validation report missing
Macromolecular Entities
Structures with similar UniProt ID
Structural Superimposition Protein Blast
Polymer Type:polypeptide(L)
Molecule:Insulin receptor
Gene (Uniprot):INSR
Chain IDs:A, C
Chain Length:719
Number of Molecules:2
Biological Source:Homo sapiens
UniProt ID:P06213 Pfam ID:PF01030, PF00757, PF00041, PF17870 EC:2.7.10.1
Structures with similar UniProt ID
Structural Superimposition Protein Blast
Polymer Type:polypeptide(L)
Molecule:Insulin receptor
Gene (Uniprot):INSR
Chain IDs:B
Chain Length:162
Number of Molecules:1
Biological Source:Homo sapiens
UniProt ID:P06213 Pfam ID:PF01030, PF00757, PF00041, PF17870 EC:2.7.10.1
Ligand Molecules
NA
Primary Citation
Antagonistic insulin mimetics lock the insulin receptor in an alternative apo-state
To Be Published ? ? ? (?)
Primary Citation of related structures
29RT
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