28ZB image
Deposition Date 2026-03-02
Release Date 2026-07-08
Last Version Date 2026-07-08
Entry Detail
PDB ID:
28ZB
Keywords:
IMMUNE SYSTEM
Title:
Crystal Structure of HLA class II major histocompatibility complex bound to HCMV-IE1 peptide
Biological Source:
Source Organism(s):
Homo sapiens (Taxon ID: 9606)
Human cytomegalovirus (Taxon ID: 10359)
Expression System(s):
Drosophila melanogaster
Method Details:
Experimental Method:
X-RAY DIFFRACTION
Resolution:
2.43 Å
R-Value Free:
0.24
R-Value Work:
0.22
R-Value Observed:
0.22
Space Group:
P 1 21 1
28ZB validation report missing
Macromolecular Entities
Structures with similar UniProt ID
Structural Superimposition Protein Blast
Polymer Type:polypeptide(L)
Molecule:HLA class II histocompatibili
Gene (Uniprot):HLA-DRA
Chain IDs:A, C (auth: D), E (auth: G), G (auth: J)
Chain Length:202
Number of Molecules:4
Biological Source:Homo sapiens
UniProt ID:P01903 Pfam ID:PF00993, PF07654
Structures with similar UniProt ID
Structural Superimposition Protein Blast
Polymer Type:polypeptide(L)
Molecule:Regulatory protein IE1,HLA cl
Gene (Uniprot):HLA-DRB1
Chain IDs:B, D (auth: E), F (auth: H), H (auth: K)
Chain Length:239
Number of Molecules:4
Biological Source:Human cytomegalovirus, Homo sapiens
UniProt ID:Q5Y7D1 Pfam ID:PF00969, PF07654
Ligand Molecules
NAG
PO4
Primary Citation
Rapid generation of Drosophila Schneider 2 (S2) cell lines and FACS-based isolation of high-yield soluble or membrane proteins.
Protein Expr.Purif. 242 106966 106966 (2026)
PMID: 42331269 DOI: 10.1016/j.pep.2026.106966
Primary Citation of related structures
28ZB
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