28XB image
Deposition Date 2026-02-25
Release Date 2026-06-24
Last Version Date 2026-06-24
Entry Detail
PDB ID:
28XB
Keywords:
GENE REGULATION
Title:
Cryo-EM structure of the human UAP56-RNA - LENG8-PCID2-SEM1 complex
Biological Source:
Source Organism(s):
Escherichia coli (Taxon ID: 562)
Homo sapiens (Taxon ID: 9606)
Expression System(s):
Escherichia coli
Method Details:
Experimental Method:
ELECTRON MICROSCOPY
Resolution:
6.20 Å
Aggregation State:
PARTICLE
Reconstruction Method:
SINGLE PARTICLE
28XB validation report missing
Macromolecular Entities
Polymer Type:polyribonucleotide
Molecule:RNA (5'-R(P*UP*UP*UP*UP*UP*U)
Chain IDs:E (auth: 1)
Chain Length:6
Number of Molecules:1
Biological Source:Homo sapiens
Structures with similar UniProt ID
Protein Blast
Polymer Type:polypeptide(L)
Molecule:Maltose/maltodextrin-binding
Gene (Uniprot):LENG8
Chain IDs:A
Chain Length:688
Number of Molecules:1
Biological Source:Escherichia coli, Homo sapiens
UniProt ID:Q96PV6 Pfam ID:PF03399
Structures with similar UniProt ID
Protein Blast
Polymer Type:polypeptide(L)
Molecule:PCI domain-containing protein
Gene (Uniprot):PCID2
Chain IDs:B
Chain Length:456
Number of Molecules:1
Biological Source:Homo sapiens
UniProt ID:Q5JVF3 Pfam ID:PF01399
Structures with similar UniProt ID
Protein Blast
Polymer Type:polypeptide(L)
Molecule:26S proteasome complex subuni
Gene (Uniprot):SEM1
Chain IDs:C
Chain Length:49
Number of Molecules:1
Biological Source:Homo sapiens
UniProt ID:P60896 Pfam ID:PF05160
Structures with similar UniProt ID
Protein Blast
Polymer Type:polypeptide(L)
Molecule:Spliceosome RNA helicase DDX3
Gene (Uniprot):DDX39B
Chain IDs:D (auth: H)
Chain Length:428
Number of Molecules:1
Biological Source:Homo sapiens
UniProt ID:Q13838 Pfam ID:PF00270, PF00271 EC:3.6.4.13
Ligand Molecules
NA
Primary Citation
Molecular basis of polyadenylated RNA fate determination in the nucleus
Nature ? ? ? (2026)
DOI: 10.1038/s41586-026-10650-0
Primary Citation of related structures
28XB
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