28UW image
Deposition Date 2026-02-20
Release Date 2026-09-02
Last Version Date 2026-09-02
Entry Detail
PDB ID:
28UW
Keywords:
PEPTIDE BINDING PROTEIN
Title:
Ternary structure of 14-3-3sigma, interaction cassette phosphopeptide, and Fusicoccin-A
Biological Source:
Source Organism(s):
Homo sapiens (Taxon ID: 9606)
synthetic construct (Taxon ID: 32630)
Expression System(s):
Escherichia coli
Method Details:
Experimental Method:
X-RAY DIFFRACTION
Resolution:
1.40 Å
R-Value Free:
0.18
R-Value Work:
0.15
R-Value Observed:
0.15
Space Group:
C 2 2 21
28UW validation report missing
Macromolecular Entities
Polymer Type:polypeptide(L)
Molecule:14-3-3 protein sigma
Chain IDs:A
Chain Length:236
Number of Molecules:1
Biological Source:Homo sapiens
Polymer Type:polypeptide(L)
Molecule:interaction cassette peptide
Chain IDs:B (auth: P)
Chain Length:15
Number of Molecules:1
Biological Source:synthetic construct
Modified Residue
Compound ID Chain ID Parent Comp ID Details 2D Image
CSO A CYS modified residue
Ligand Molecules
CL
MG
SIT
Primary Citation
Molecular Glue and Phosphorylation-Dependent 14-3-3 Recruitment to p53 with an Engineered Interaction Cassette.
Acs Chem.Biol. ? ? ? (2026)
PMID: 42631642 DOI: 10.1021/acschembio.6c00482
Primary Citation of related structures
28UW
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