ISDA: 28OA

Deposition Date 2026-02-10

Release Date 2026-08-12

Last Version Date 2026-08-12

Entry Detail

PDB ID:

28OA

Keywords:

MEMBRANE PROTEIN

Title:

Closed state Escherichia coli MscL mechanosensitive channel in DMPC nanodiscs

Biological Source:

Source Organism(s):

Escherichia coli (Taxon ID: 562)

Expression System(s):

Escherichia coli bl21(de3)

Method Details:

Experimental Method:

ELECTRON MICROSCOPY

Resolution:

4.10 Å

Aggregation State:

PARTICLE

Reconstruction Method:

SINGLE PARTICLE

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Macromolecular Entities

Polymer Type:polypeptide(L)
Molecule:Large-conductance mechanosens
Chain IDs:A, B (auth: C), C (auth: D), D (auth: E), E (auth: B)
Chain Length:142
Number of Molecules:5
Biological Source:Escherichia coli

Ligand Molecules

Primary Citation

Structural basis of the gating mechanism of the large-conductance mechanosensitive channel from Escherichia coli

Hardman, K, Wort, J.L, Waheed, Q, Liu, X, Arul, D, Porav, S.A, Calabrese, A.N, Muench, S.P, Pliotas, C.Show

Nat Comm ? ? ? (2026)

DOI: 10.1038/s41467-026-76193-0

Primary Citation of related structures

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