ISDA: 28JF

Deposition Date 2026-02-03

Release Date 2026-08-26

Last Version Date 2026-08-26

Entry Detail

PDB ID:

28JF

Keywords:

ANTIVIRAL PROTEIN

Title:

BKPyV VP1 IN COMPLEX WITH VHH016

Biological Source:

Source Organism(s):

Betapolyomavirus hominis (Taxon ID: 1891762)
Lama glama (Taxon ID: 9844)

Expression System(s):

Escherichia coli bl21

Method Details:

Experimental Method:

X-RAY DIFFRACTION

Resolution:

2.59 Å

R-Value Free:

0.23

R-Value Work:

0.21

Space Group:

P 1 21 1

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Macromolecular Entities

Polymer Type:polypeptide(L)
Molecule:Capsid protein VP1
Mutagens:S104C
Chain IDs:A, B, C, D, E, K (auth: L), L (auth: M), M (auth: N), N (auth: O), O (auth: P)
Chain Length:273
Number of Molecules:10
Biological Source:Betapolyomavirus hominis

Polymer Type:polypeptide(L)
Molecule:VHH016
Chain IDs:F, G, H, I, J, P (auth: Q), Q (auth: R), R (auth: S), S (auth: T), T (auth: U)
Chain Length:124
Number of Molecules:10
Biological Source:Lama glama

Ligand Molecules

Primary Citation

Natural and patient-derived mutations in BK polyomavirus VP1 reveal structural determinants of BC-loop dependent antibody escape

Akkermans, O, Ubeda Nicolau, C, Bandara, A, Correa Sierra, C, Martins, F, De Graef, S, Deans, E, Ross, S, Sienaert, S, Galindo Cerrada, M, Chitalia, V, Mani, N, Weeks, S, Munawar, A.Show

To Be Published ? ? ? (?)

Primary Citation of related structures

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