ISDA: 28HW

Deposition Date 2026-01-30

Release Date 2026-09-16

Last Version Date 2026-09-16

Entry Detail

PDB ID:

28HW

Keywords:

SUGAR BINDING PROTEIN

Title:

Crystal structure of the human galectin-3 carbohydrate-recognition domain in complex with p-Methoxyphenyl 3-O-benzyl-beta-D-galactopyranoside

Biological Source:

Source Organism(s):

Homo sapiens (Taxon ID: 9606)

Expression System(s):

Escherichia coli

Method Details:

Experimental Method:

X-RAY DIFFRACTION

Resolution:

1.10 Å

R-Value Free:

0.18

R-Value Work:

0.17

R-Value Observed:

0.17

Space Group:

P 21 21 21

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Macromolecular Entities

Structures with similar UniProt ID

Structural Superimposition Protein Blast

Polymer Type:polypeptide(L)
Molecule:Galectin-3
Gene (Uniprot):LGALS3
Chain IDs:A
Chain Length:142
Number of Molecules:1
Biological Source:Homo sapiens

UniProt ID:P17931 Pfam ID:PF00337

Ligand Molecules

A1J0D

Primary Citation

Exploring the selectivity of molecules targeting the carbohydrate binding site in galectins

Silvestri, I, Filocaso, M, Capasso, D, Iadonisi, A, Di Gaetano, S, Pirone, L, Saviano, M, Pedone, E.M.Show

Sci Rep ? ? ? (2026)

DOI: 10.1038/s41598-026-69841-4

Primary Citation of related structures

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