ISDA: 27IV

Deposition Date 2026-06-03

Release Date 2026-09-02

Last Version Date 2026-09-02

Entry Detail

PDB ID:

27IV

Keywords:

HYDROLASE

Title:

Crystal structure of the mature form of human ASPRV1 bound to self-cleavage peptide

Biological Source:

Source Organism(s):

Homo sapiens (Taxon ID: 9606)

Expression System(s):

Escherichia coli bl21(de3)

Method Details:

Experimental Method:

X-RAY DIFFRACTION

Resolution:

1.95 Å

R-Value Free:

0.23

R-Value Work:

0.19

R-Value Observed:

0.19

Space Group:

P 21 21 21

Download Validation Report

Macromolecular Entities

Structures with similar UniProt ID

Structural Superimposition Protein Blast

Polymer Type:polypeptide(L)
Molecule:Retroviral-like aspartic prot
Gene (Uniprot):ASPRV1
Chain IDs:A (auth: B), B (auth: A)
Chain Length:142
Number of Molecules:2
Biological Source:Homo sapiens

UniProt ID:Q53RT3 Pfam ID:PF13975 EC:3.4.23.-

Ligand Molecules

Primary Citation

Structure and enzymatic properties of human retroviral-like aspartic protease 1 and functional roles of disease-associated mutations.

Feng, X, Chen, Z, Lan, C, Ding, J.Show

Acta Biochim.Biophys.Sin. ? ? ? (2026)

PMID: 42593882 DOI: 10.3724/abbs.2026141

Primary Citation of related structures

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