27IQ image
Deposition Date 2026-06-03
Release Date 2026-09-02
Last Version Date 2026-09-02
Entry Detail
PDB ID:
27IQ
Keywords:
HYDROLASE
Title:
Crystal structure of the mature form of human ASPRV1 bound to filaggrin peptide
Biological Source:
Source Organism(s):
Homo sapiens (Taxon ID: 9606)
Expression System(s):
Escherichia coli bl21(de3)
Method Details:
Experimental Method:
X-RAY DIFFRACTION
Resolution:
2.09 Å
R-Value Free:
0.29
R-Value Work:
0.26
R-Value Observed:
0.26
Space Group:
P 21 21 21
27IQ validation report missing
Macromolecular Entities
Structures with similar UniProt ID
Structural Superimposition Protein Blast
Polymer Type:polypeptide(L)
Molecule:Retroviral-like aspartic prot
Gene (Uniprot):ASPRV1
Chain IDs:A, B
Chain Length:142
Number of Molecules:2
Biological Source:Homo sapiens
UniProt ID:Q53RT3 Pfam ID:PF13975 EC:3.4.23.-
Ligand Molecules
CA
Primary Citation
Structure and enzymatic properties of human retroviral-like aspartic protease 1 and functional roles of disease-associated mutations.
Acta Biochim.Biophys.Sin. ? ? ? (2026)
PMID: 42593882 DOI: 10.3724/abbs.2026141
Primary Citation of related structures
27IQ
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