26NL image
Deposition Date 2026-05-07
Release Date 2026-07-22
Last Version Date 2026-07-22
Entry Detail
PDB ID:
26NL
Keywords:
VIRAL PROTEIN
Title:
Cryo-EM Structure of the HIV Capsid in Complex with VHL-3
Biological Source:
Source Organism(s):
Human immunodeficiency virus 1 (Taxon ID: 11676)
synthetic construct (Taxon ID: 32630)
Expression System(s):
Escherichia coli
Method Details:
Experimental Method:
ELECTRON MICROSCOPY
Resolution:
2.80 Å
Aggregation State:
PARTICLE
Reconstruction Method:
SINGLE PARTICLE
26NL validation report missing
Macromolecular Entities
Structures with similar UniProt ID
Structural Superimposition Protein Blast
Polymer Type:polypeptide(L)
Molecule:Capsid protein p24
Gene (Uniprot):gag-pol
Chain IDs:A, B, C, D, E, F
Chain Length:231
Number of Molecules:6
Biological Source:Human immunodeficiency virus 1
UniProt ID:P0C6F2
Structural Superimposition Protein Blast
Polymer Type:polypeptide(D)
Molecule:2LZ-WFP-A1E9U-BAL-TBG-HYP
Chain IDs:G, H, I, J, K, L
Chain Length:6
Number of Molecules:6
Biological Source:synthetic construct
Ligand Molecules
A1E9V
Primary Citation
Revolutionizing Anti-HIV Therapy: Targeted Degradation of Capsid by Host-Hijacking PROTAC Overcomes Drug Resistance
To Be Published ? ? ? (?)
Primary Citation of related structures
26NL
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