26FV image
Deposition Date 2026-04-29
Release Date 2026-09-09
Last Version Date 2026-09-09
Entry Detail
PDB ID:
26FV
Keywords:
LYASE
Title:
Tetrameric cystathionine beta-synthase of Mycobacterium tuberculosis bound to AOAA
Biological Source:
Source Organism(s):
Mycobacterium tuberculosis H37Rv (Taxon ID: 83332)
Expression System(s):
Escherichia coli bl21(de3)
Method Details:
Experimental Method:
ELECTRON MICROSCOPY
Resolution:
3.34 Å
Aggregation State:
PARTICLE
Reconstruction Method:
SINGLE PARTICLE
26FV validation report missing
Macromolecular Entities
Structures with similar UniProt ID
Structural Superimposition Protein Blast
Polymer Type:polypeptide(L)
Molecule:Probable cystathionine beta-s
Gene (Uniprot):cbs
Chain IDs:A, B, C, D
Chain Length:478
Number of Molecules:4
Biological Source:Mycobacterium tuberculosis H37Rv
UniProt ID:P9WP51 Pfam ID:PF00291, PF00571 EC:4.2.1.22
Ligand Molecules
IK2
Primary Citation
Molecular insights into inhibitor action on the catalytic activity of Mycobacterium tuberculosis cystathionine beta-synthase enzyme.
Int.J.Biol.Macromol. 381 154013 154013 (2026)
PMID: 42575362 DOI: 10.1016/j.ijbiomac.2026.154013
Primary Citation of related structures
26FV
Feedback Form
Name
Email
Institute
Feedback