25HR image
Deposition Date 2026-04-03
Release Date 2026-08-12
Last Version Date 2026-08-12
Entry Detail
PDB ID:
25HR
Keywords:
ANTIBIOTIC
Title:
Cryo-EM structure of Pseudomonas aeruginosa FtsQBLWI in complex with imipenem
Biological Source:
Source Organism(s):
Pseudomonas aeruginosa PAO1 (Taxon ID: 208964)
Expression System(s):
Escherichia coli bl21(de3)
Method Details:
Experimental Method:
ELECTRON MICROSCOPY
Resolution:
3.60 Å
Aggregation State:
PARTICLE
Reconstruction Method:
SINGLE PARTICLE
25HR validation report missing
Macromolecular Entities
Polymer Type:polypeptide(L)
Molecule:Probable peptidoglycan glycos
Chain IDs:D (auth: A)
Chain Length:399
Number of Molecules:1
Biological Source:Pseudomonas aeruginosa PAO1
Polymer Type:polypeptide(L)
Molecule:Peptidoglycan D,D-transpeptid
Chain IDs:E (auth: B)
Chain Length:579
Number of Molecules:1
Biological Source:Pseudomonas aeruginosa PAO1
Polymer Type:polypeptide(L)
Molecule:Cell division protein FtsQ
Chain IDs:A (auth: C)
Chain Length:287
Number of Molecules:1
Biological Source:Pseudomonas aeruginosa PAO1
Polymer Type:polypeptide(L)
Molecule:Cell division protein FtsL
Chain IDs:B (auth: D)
Chain Length:97
Number of Molecules:1
Biological Source:Pseudomonas aeruginosa PAO1
Polymer Type:polypeptide(L)
Molecule:Cell division protein FtsB
Chain IDs:C (auth: E)
Chain Length:94
Number of Molecules:1
Biological Source:Pseudomonas aeruginosa PAO1
Ligand Molecules
A1H3N
Primary Citation
Structural, functional, and mechanistic studies of the bacterial divisome FtsWIQBL in complex with antibiotics.
Structure ? ? ? (2026)
PMID: 42537644 DOI: 10.1016/j.str.2026.07.005
Primary Citation of related structures
25HR
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