25GN image
Deposition Date 2026-04-02
Release Date 2026-08-26
Last Version Date 2026-08-26
Entry Detail
PDB ID:
25GN
Keywords:
MEMBRANE PROTEIN
Title:
receptor-arrestin
Biological Source:
Source Organism(s):
Homo sapiens (Taxon ID: 9606)
Expression System(s):
Trichoplusia ni
Method Details:
Experimental Method:
ELECTRON MICROSCOPY
Resolution:
3.20 Å
Aggregation State:
PARTICLE
Reconstruction Method:
SINGLE PARTICLE
25GN validation report missing
Macromolecular Entities
Polymer Type:polypeptide(L)
Molecule:Isoform 1B of Beta-arrestin-1
Chain IDs:A (auth: C)
Chain Length:410
Number of Molecules:1
Biological Source:Homo sapiens
Polymer Type:polypeptide(L)
Molecule:heavy chain of scFv30
Chain IDs:B (auth: H)
Chain Length:121
Number of Molecules:1
Biological Source:Homo sapiens
Polymer Type:polypeptide(L)
Molecule:light chain of scFv30
Chain IDs:C (auth: L)
Chain Length:108
Number of Molecules:1
Biological Source:Homo sapiens
Polymer Type:polypeptide(L)
Molecule:Frizzled-6
Chain IDs:D (auth: R)
Chain Length:524
Number of Molecules:1
Biological Source:Homo sapiens
Ligand Molecules
NA
Primary Citation
Direct beta-arrestin engagement by the non-canonical WNT receptor FZD6 via a shallow binding pocket
Acta Pharmacol.Sin. ? ? ? (2026)
DOI: 10.1038/s41401-026-01902-w
Primary Citation of related structures
25GN
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