ISDA: 24YQ

Deposition Date 2026-03-24

Release Date 2026-08-26

Last Version Date 2026-09-16

Entry Detail

PDB ID:

24YQ

Keywords:

OXIDOREDUCTASE

Title:

Crystal structure of Enoyl-ACP reducatase FabV from Peterkaempfera bronchialis with NADH cofactor

Biological Source:

Source Organism(s):

Peterkaempfera bronchialis (Taxon ID: 2126346)

Expression System(s):

Escherichia coli bl21(de3)

Method Details:

Experimental Method:

X-RAY DIFFRACTION

Resolution:

1.96 Å

R-Value Free:

0.29

R-Value Work:

0.23

R-Value Observed:

0.24

Space Group:

P 1 21 1

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Macromolecular Entities

Structures with similar UniProt ID

Structural Superimposition Protein Blast

Polymer Type:polypeptide(L)
Molecule:trans-2-enoyl-CoA reductase (
Gene (Uniprot):fabV
Chain IDs:A, B
Chain Length:417
Number of Molecules:2
Biological Source:Peterkaempfera bronchialis

UniProt ID:A0A345SU67 Pfam ID:PF12242, PF12241, PF07055 EC:1.3.1.44

Ligand Molecules

NAI

Primary Citation

Iterative Enoyl Reduction by a FabV-Family Enzyme Expands the Chemical Landscape of Discrete Polyketide Synthases.

Gao, Y, Jiang, K, Dai, Y, Chen, H, Wang, Q, Li, D, Yan, X, Wei, G, Lin, Z, Chen, H, Deng, Z, Qu, X.Show

J.Am.Chem.Soc. 148 36152 36164 (2026)

PMID: 42677584 DOI: 10.1021/jacs.6c11267

Primary Citation of related structures

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