24VN image
Deposition Date 2026-03-22
Release Date 2026-08-12
Last Version Date 2026-08-12
Entry Detail
PDB ID:
24VN
Keywords:
MEMBRANE PROTEIN
Title:
Cryo-EM structure of the human wild-type KCNQ2/KCNQ3 heterotetramer (2:2 stoichiometry) in apo state (M2323 WT, without symmetry expansion)
Biological Source:
Source Organism(s):
Homo sapiens (Taxon ID: 9606)
Aequorea victoria (Taxon ID: 6100)
Expression System(s):
Homo sapiens
Method Details:
Experimental Method:
ELECTRON MICROSCOPY
Resolution:
3.58 Å
Aggregation State:
PARTICLE
Reconstruction Method:
SINGLE PARTICLE
24VN validation report missing
Macromolecular Entities
Polymer Type:polypeptide(L)
Molecule:Potassium voltage-gated chann
Chain IDs:A, B (auth: C)
Chain Length:892
Number of Molecules:2
Biological Source:Homo sapiens
Polymer Type:polypeptide(L)
Molecule:Green fluorescent protein,Pot
Chain IDs:C (auth: B), D
Chain Length:1142
Number of Molecules:2
Biological Source:Aequorea victoria, Homo sapiens
Ligand Molecules
9PE
YJ0
Primary Citation
Structural basis for heteromeric assembly and subthreshold activation of human M-channel
Vita ? ? ? (2026)
DOI: 10.15302/vita.2026.05.0032
Primary Citation of related structures
24VN
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