24VK image
Deposition Date 2026-03-22
Release Date 2026-08-12
Last Version Date 2026-08-12
Entry Detail
PDB ID:
24VK
Keywords:
MEMBRANE PROTEIN
Title:
Cryo-EM structure of the human KCNQ2/KCNQ3 heterotetramer (3:1 stoichiometry) with CLM142 and PIP2 in open state (M2223 open, without symmetry expansion)
Biological Source:
Source Organism(s):
Homo sapiens (Taxon ID: 9606)
Aequorea victoria (Taxon ID: 6100)
Expression System(s):
Homo sapiens
Method Details:
Experimental Method:
ELECTRON MICROSCOPY
Resolution:
3.75 Å
Aggregation State:
PARTICLE
Reconstruction Method:
SINGLE PARTICLE
24VK validation report missing
Macromolecular Entities
Polymer Type:polypeptide(L)
Molecule:Potassium voltage-gated chann
Chain IDs:A
Chain Length:620
Number of Molecules:1
Biological Source:Homo sapiens
Polymer Type:polypeptide(L)
Molecule:Green fluorescent protein,Pot
Chain IDs:B, C (auth: D), D (auth: C)
Chain Length:753
Number of Molecules:3
Biological Source:Aequorea victoria, Homo sapiens
Ligand Molecules
A1E7E
PIO
Primary Citation
Structural basis for heteromeric assembly and subthreshold activation of human M-channel
Vita ? ? ? (2026)
DOI: 10.15302/vita.2026.05.0032
Primary Citation of related structures
24VK
Feedback Form
Name
Email
Institute
Feedback