24VJ image
Deposition Date 2026-03-22
Release Date 2026-08-12
Last Version Date 2026-08-12
Entry Detail
PDB ID:
24VJ
Keywords:
MEMBRANE PROTEIN
Title:
Cryo-EM structure of the human KCNQ2/KCNQ3 heterotetramer (3:1 stoichiometry) with CLM142 (M2223 CLM142, without symmetry expansion)
Biological Source:
Source Organism(s):
Homo sapiens (Taxon ID: 9606)
Aequorea victoria (Taxon ID: 6100)
Expression System(s):
Homo sapiens
Method Details:
Experimental Method:
ELECTRON MICROSCOPY
Resolution:
3.07 Å
Aggregation State:
PARTICLE
Reconstruction Method:
SINGLE PARTICLE
24VJ validation report missing
Macromolecular Entities
Polymer Type:polypeptide(L)
Molecule:Potassium voltage-gated chann
Chain IDs:A
Chain Length:620
Number of Molecules:1
Biological Source:Homo sapiens
Polymer Type:polypeptide(L)
Molecule:Green fluorescent protein,Pot
Chain IDs:B, C, D
Chain Length:753
Number of Molecules:3
Biological Source:Aequorea victoria, Homo sapiens
Ligand Molecules
9PE
A1E7E
YJ0
Primary Citation
Structural basis for heteromeric assembly and subthreshold activation of human M-channel
Vita ? ? ? (2026)
DOI: 10.15302/vita.2026.05.0032
Primary Citation of related structures
24VJ
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