ISDA: 23NX

Deposition Date 2026-02-11

Release Date 2026-08-19

Last Version Date 2026-08-19

Entry Detail

PDB ID:

23NX

Keywords:

TRANSFERASE

Title:

Structure of mouse DNMT3A-TCL1A complex

Biological Source:

Source Organism(s):

Mus musculus (Taxon ID: 10090)

Expression System(s):

Spodoptera frugiperda

Method Details:

Experimental Method:

ELECTRON MICROSCOPY

Resolution:

3.32 Å

Aggregation State:

PARTICLE

Reconstruction Method:

SINGLE PARTICLE

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Macromolecular Entities

Polymer Type:polypeptide(L)
Molecule:T-cell leukemia/lymphoma prot
Chain IDs:A, B (auth: C), C (auth: D), D (auth: E)
Chain Length:116
Number of Molecules:4
Biological Source:Mus musculus

Polymer Type:polypeptide(L)
Molecule:DNA (cytosine-5)-methyltransf
Chain IDs:E (auth: B), F
Chain Length:835
Number of Molecules:2
Biological Source:Mus musculus

Ligand Molecules

Primary Citation

Cryo-EM structure of the murine DNMT3A-TCL1A complex.

Li, W, Liu, Q, Li, J, Wang, X, He, G, Guo, L.Show

J.Struct.Biol. 218 108352 108352 (2026)

PMID: 42546996 DOI: 10.1016/j.jsb.2026.108352

Primary Citation of related structures

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