ISDA: 23FU

Deposition Date 2026-02-05

Release Date 2026-08-12

Last Version Date 2026-08-12

Entry Detail

PDB ID:

23FU

Keywords:

NUCLEAR PROTEIN/DNA

Title:

Cryo-EM structure of Chaetomium thermophilum RSC bound to a nucleosome

Biological Source:

Source Organism(s):

Xenopus laevis (Taxon ID: 8355)
synthetic construct (Taxon ID: 32630)
Thermochaetoides thermophila DSM 1495 (Taxon ID: 759272)

Expression System(s):

Escherichia coli, Homo sapiens

Method Details:

Experimental Method:

ELECTRON MICROSCOPY

Resolution:

4.45 Å

Aggregation State:

PARTICLE

Reconstruction Method:

SINGLE PARTICLE

Download Validation Report

Macromolecular Entities

Polymer Type:polypeptide(L)
Molecule:Histone H3
Chain IDs:A, E
Chain Length:135
Number of Molecules:2
Biological Source:Xenopus laevis

Polymer Type:polypeptide(L)
Molecule:Histone H4
Chain IDs:B, F
Chain Length:102
Number of Molecules:2
Biological Source:Xenopus laevis

Polymer Type:polypeptide(L)
Molecule:Histone H2A
Chain IDs:C, G
Chain Length:129
Number of Molecules:2
Biological Source:Xenopus laevis

Polymer Type:polypeptide(L)
Molecule:Histone H2B
Chain IDs:D, H
Chain Length:125
Number of Molecules:2
Biological Source:Xenopus laevis

Polymer Type:polydeoxyribonucleotide
Molecule:DNA (167-MER)
Chain IDs:I
Chain Length:167
Number of Molecules:1
Biological Source:synthetic construct

Polymer Type:polydeoxyribonucleotide
Molecule:DNA (167-MER)
Chain IDs:J
Chain Length:167
Number of Molecules:1
Biological Source:synthetic construct

Polymer Type:polypeptide(L)
Molecule:WD40 repeat-containing protei
Chain IDs:K
Chain Length:1595
Number of Molecules:1
Biological Source:Thermochaetoides thermophila DSM 1495

Polymer Type:polypeptide(L)
Molecule:Putative chromatin structure
Chain IDs:L
Chain Length:733
Number of Molecules:1
Biological Source:Thermochaetoides thermophila DSM 1495

Polymer Type:polypeptide(L)
Molecule:Actin-related protein 4
Chain IDs:M
Chain Length:476
Number of Molecules:1
Biological Source:Thermochaetoides thermophila DSM 1495

Polymer Type:polypeptide(L)
Molecule:Ssr1
Chain IDs:N, O
Chain Length:694
Number of Molecules:2
Biological Source:Thermochaetoides thermophila DSM 1495

Polymer Type:polypeptide(L)
Molecule:DM2 domain-containing protein
Chain IDs:P
Chain Length:547
Number of Molecules:1
Biological Source:Thermochaetoides thermophila DSM 1495

Polymer Type:polypeptide(L)
Molecule:DUF1750-domain-containing pro
Chain IDs:Q
Chain Length:769
Number of Molecules:1
Biological Source:Thermochaetoides thermophila DSM 1495

Polymer Type:polypeptide(L)
Molecule:Putative chromatin structure-
Chain IDs:R
Chain Length:763
Number of Molecules:1
Biological Source:Thermochaetoides thermophila DSM 1495

Polymer Type:polypeptide(L)
Molecule:Putative chromatin structure-
Chain IDs:S
Chain Length:607
Number of Molecules:1
Biological Source:Thermochaetoides thermophila DSM 1495

Polymer Type:polypeptide(L)
Molecule:Rsc7
Chain IDs:T
Chain Length:534
Number of Molecules:1
Biological Source:Thermochaetoides thermophila DSM 1495

Polymer Type:polypeptide(L)
Molecule:Rsc1
Chain IDs:U
Chain Length:991
Number of Molecules:1
Biological Source:Thermochaetoides thermophila DSM 1495

Polymer Type:polypeptide(L)
Molecule:Rsc58
Chain IDs:V
Chain Length:990
Number of Molecules:1
Biological Source:Thermochaetoides thermophila DSM 1495

Ligand Molecules

ADP

Primary Citation

Structural principles underlying the evolution of SWI/SNF chromatin remodelers

Ma, S.S, Liu, M.D, Xu, W.C, Wang, Q.M, Wang, X.M, Huang, Y.G, Li, M.C, Li, C.H, Shen, Q.T, Chen, Y.Show

Sci Adv ? ? ? (2026)

Primary Citation of related structures

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