ISDA: 23FE

Deposition Date 2026-02-04

Release Date 2026-08-26

Last Version Date 2026-08-26

Entry Detail

PDB ID:

23FE

Keywords:

NUCLEAR PROTEIN

Title:

Cryo-EM structure of human ATR-ATRIP complex with ATPgammaS, Chk1 and ETAA1

Biological Source:

Source Organism(s):

Homo sapiens (Taxon ID: 9606)

Expression System(s):

Homo sapiens, Spodoptera frugiperda

Method Details:

Experimental Method:

ELECTRON MICROSCOPY

Resolution:

2.90 Å

Aggregation State:

PARTICLE

Reconstruction Method:

SINGLE PARTICLE

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Macromolecular Entities

Polymer Type:polypeptide(L)
Molecule:Serine/threonine-protein kina
Chain IDs:A, B
Chain Length:2644
Number of Molecules:2
Biological Source:Homo sapiens

Polymer Type:polypeptide(L)
Molecule:ATR-interacting protein
Chain IDs:G (auth: C), H (auth: D)
Chain Length:791
Number of Molecules:2
Biological Source:Homo sapiens

Polymer Type:polypeptide(L)
Molecule:Serine/threonine-protein kina
Chain IDs:C (auth: E), D (auth: F)
Chain Length:14
Number of Molecules:2
Biological Source:Homo sapiens

Polymer Type:polypeptide(L)
Molecule:Ewing's tumor-associated anti
Chain IDs:E (auth: G), F (auth: H)
Chain Length:250
Number of Molecules:2
Biological Source:Homo sapiens

Ligand Molecules